The Heart of Africa Group is a larger network of investigators researching cardiovascular conditions prevalent to the African continent. This group originated at the Soweto Cardiovascular Research Unit (University of Witwatersrand) and was expanded from the landmark “Heart of Soweto Study” which investigated the prevalence, presentation and management of cardiac disease in more than 8000 patients from Soweto, South Africa.
The Heart of Africa Group (based at the University of Cape Town) initiated several cohort studies investigating the impact of HIV/AIDS on cardiovascular disease, the prevalence of rheumatic heart disease diagnosed in adulthood and the spectrum of conditions leading to heart failure, amongst others, and paved the way for many other African cardiovascular disease studies. These multi-centre, multi-country studies are carried out in several African countries, including Mozambique, Nigeria, Cameroon, Tanzania, Kenya and Sudan. This group has also initiated and leads global trials, most recently the World Heart Federation COVID-19 & Cardiovascular Disease Study (> 25 countries, 5000 patients).